tag:blogger.com,1999:blog-9430835.post1405972392615784960..comments2024-03-28T16:22:14.888-07:00Comments on Steve Sailer: iSteve: Breaking News: Your genes didn't evolve to kill youUnknownnoreply@blogger.comBlogger14125tag:blogger.com,1999:blog-9430835.post-78389853730302848952009-04-17T12:01:00.000-07:002009-04-17T12:01:00.000-07:00"Your genes didn't evolve to kill you."
Question:..."Your genes didn't evolve to kill you."<br /><br />Question: Who is the "you?" Genes may operate at a personal level, but they do not evolve that way. Suppose that a certain gene is lethal to 0.00001% of the population, but is otherwise beneficial to the other 99.99999%. Did that gene evolve to kill anyone, even an unfortunate small percentage?Epicureannoreply@blogger.comtag:blogger.com,1999:blog-9430835.post-3407698196161628262009-04-16T18:46:00.000-07:002009-04-16T18:46:00.000-07:00"your genes evolved to help you survive and reprod..."your genes evolved to help you survive and reproduce"<br /><br />I'm curious. What is the survival value of male pattern baldness?roger rogainenoreply@blogger.comtag:blogger.com,1999:blog-9430835.post-39461468996272210882009-04-16T13:47:00.000-07:002009-04-16T13:47:00.000-07:00I remember reading a few years ago that a small nu...I remember reading a few years ago that a small number of scientists believed that cancer was the result of extreme deficiency of certain nutrients.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-9430835.post-45254818524523989332009-04-16T11:41:00.000-07:002009-04-16T11:41:00.000-07:00One man's taxes are another man's greens fees.One man's taxes are another man's greens fees.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-9430835.post-68406073968252326262009-04-16T09:50:00.000-07:002009-04-16T09:50:00.000-07:00Your genes did not evolve to kill you before you r...Your genes did not evolve to kill you <I>before you reproduce</I> -- but it's not such a stretch to imagine genes that evolved to kill you at the age of fifty to seventy, when in tribal societies you'd be a net drain on social welfare but in modern societies you'd really rather not drop dead.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-9430835.post-20606260853870682692009-04-16T08:49:00.000-07:002009-04-16T08:49:00.000-07:00When I was in college in the late 90s. "Genetic co...When I was in college in the late 90s. "Genetic counselor" was one of the hot new career fields.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-9430835.post-13283819114070293362009-04-16T04:29:00.000-07:002009-04-16T04:29:00.000-07:00If a disease strikes after reproductive age, does ...<I>If a disease strikes after reproductive age, does it diminish Darwinian fitness? Probably, but only through family survival effects which are weaker than direct reproduction. So old-age diseases, which is what most health dollars are spent on, may well be correlated with genes.</I>Chief, your missing something big. Pathogens evolve too.robnoreply@blogger.comtag:blogger.com,1999:blog-9430835.post-1294986914507344302009-04-16T00:53:00.000-07:002009-04-16T00:53:00.000-07:00Don't forget about alleles that are advantageous i...Don't forget about alleles that are advantageous in the heterozygous state. Sickle cell anemia is the classic example for this. There is also speculation that cystic fibrosis is similar in this sense. Having only one allele for cystic fibrosis might confer some advantage.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-9430835.post-27725382160419350682009-04-15T23:35:00.000-07:002009-04-15T23:35:00.000-07:00A lot of the human genome hype about improving med...A lot of the human genome hype about improving medicine was always pure hype, but it's important to understand why.<br /><br />For instance, we know all there is to know about the genetics of cystic fibrosis, and are no closer to a cure. What made anyone think whole genome scans would help with more complicated diseases like cancer?<br /><br />The truth is that a lot of people made money from the bubble built around inflated medical hopes, but there were a lot more Levis and Wells Fargos than people panning for gold.<br /><br />Companies like Affymetrix have sold expensive microarrays to universities and government labs, and there's been a huge bioinformatics push by giants like IBM to sell hardware and software to the same groups. Academics from biologists, computer scientists, and statisticians have published hundreds of papers on intermediate technical problems.<br /><br />That's by design, and that's why the NIH so lavishly funds genomics research. It's a form of Keynesianism or industrial policy, just like a lot of defense spending and prison construction.<br /><br />The problem is our leaders and media don't like to admit that's how we run our economy, although big bailouts make it harder to conceal. Republicans particularly won't admit that big companies sometimes succeed because of the state sector.<br /><br />When politicians want to support biotech hubs in their districts, they tell the public they're spending tax dollars to cure cancer. Who could object?<br /><br />My problem actually isn't with our de facto Keynesianism. It would just be more effective and less corrupted by special interests if it wasn't always masked as something else.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-9430835.post-87088302335896064172009-04-15T22:58:00.000-07:002009-04-15T22:58:00.000-07:00It's not as obvious as you make it seem that hopes...It's not as obvious as you make it seem that hopes were elusive because "your genes didn't evolve to kill you," as explained by Wade:<br /><br />"Unlike the rare diseases caused by a change affecting only one gene, common diseases like cancer and diabetes are caused by a set of several genetic variations in each person. Since these common diseases generally strike later in life, after people have had children, the theory has been that natural selection is powerless to weed them out."Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-9430835.post-86060048877541881802009-04-15T22:34:00.000-07:002009-04-15T22:34:00.000-07:00Pie Hole said,
"Cochran is an insufferable knowi...Pie Hole said, <br /><br />"Cochran is an insufferable knowitall. But hey the man does know a hell of a lot."<br /><br />Maybe I just have a thing for brainy science types, but Cochran's insufferability is matched...no, is *surpassed* by his sense of humor. He's a pussycat underneath it all. It takes a woman to see that, boys.Sharanoreply@blogger.comtag:blogger.com,1999:blog-9430835.post-3833264993446489042009-04-15T21:53:00.000-07:002009-04-15T21:53:00.000-07:00BTW, Steve, what's the best way to donate anonymou...BTW, Steve, what's the best way to donate anonymously to VDare? Or is that crime think? Seriously, someone's got to combat the numb-nuts at SPLC who never miss a chance to compare anyone who's anti-immigration with a lynch mob.Chief Seattlenoreply@blogger.comtag:blogger.com,1999:blog-9430835.post-51875450898671495632009-04-15T21:50:00.000-07:002009-04-15T21:50:00.000-07:00To the credit of the genome researchers, the same ...To the credit of the genome researchers, the same tools to quickly sequence Human DNA work just as well on pathogen DNA. <br /><br />If a disease strikes after reproductive age, does it diminish Darwinian fitness? Probably, but only through family survival effects which are weaker than direct reproduction. So old-age diseases, which is what most health dollars are spent on, may well be correlated with genes. <br /><br />Also, fitness is a combination of genes plus environment, and the modern environment hasn't been around long. Type II diabetes is a huge problem today. But 500 years ago, packing on the pounds in good times was probably a good idea in most parts of the world.Chief Seattlenoreply@blogger.comtag:blogger.com,1999:blog-9430835.post-28492972098297951562009-04-15T21:47:00.000-07:002009-04-15T21:47:00.000-07:00Cochran is an insufferable knowitall. But hey the ...Cochran is an insufferable knowitall. But hey the man does know a hell of a lot. <br /><br />And he is right about the undercounting of diseases actually caused by as yet to be determined infections. Someday he will get much wider recognition for his work in this area.Pie Holenoreply@blogger.com