The Cochran-Ewald theory that many chronic diseases are caused by cryptic infections makes a lot of sense from an evolutionary standpoint, but, it is extremely hard to find the killer germs. Fortunately, Matthew Meyerson, a geneticist at Harvard and Dana-Farber is working on a new approach to looking for germs:
Discovery of pathogenic microbes: We have developed a genomic approach to discover microbial sequences in cryptic infectious diseases. In sequence-based computational subtraction, we generate and sequence libraries from diseased tissues. Sequences that match the human genome are removed computationally, leaving microbial sequences (Weber et al., 2002). We have recently generated several genomic representational methods to complement this pathogen discovery approach and are applying the methods to human disease samples.
My published articles are archived at iSteve.com -- Steve Sailer
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